About the research topic

This project aims to develop methods to quantify microvascular perfusion in Digital Subtraction Angiography (DSA) images during endovascular treatment. In our approach, the replacement of the recanalization concept with a measure of microvascular reperfusion is a major innovation. In the first part of the project, we will investigate perfusion biomarkers that can potentially be quantified based on projection imaging. Simultaneously, we will study which perfusion parameters are most relevant in clinical practice. The results of both initial studies will guide the development of quantitative imaging biomarkers from interventional angiographies. In the final year, the imaging biomarkers developed will be validated using clinical data.

Funding: Health Holland, Philips

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