Open projects

We have several open research projects for MSc students who want to do an internship or graduation project. We keep these projects in a portfolio document: BIGR MSc Project Portfolio. In general, the projects focus on medical image processing.

Applied Medical Image Analysis

Neuroimage Analysis & Machine Learning

  • Frontotemporal dementia (FTD) is a type of dementia that has a debilitating effect on patients and their caregivers. About 20% of patients have genetic FTD caused by known pathogenetic mutations. For the other patients, who have sporadic FTD, diagnosis is slow (~4 years) with frequent misdiagnosis due to clinical, genetic and molecular heterogeneity. Thus, there is an urgent need for biomarkers that improve diagnosis of sporadic FTD and its pathological subtypes. Artificial intelligence is expected to play a key role here, driven by its expanding role in the medical field, in particular radiology, in combination with the growth of clinical data and medical imaging made available for medical research. This project focuses on the diagnosis of FTD by validating a comprehensive set of liquid and imaging biomarkers and developing an AI-driven diagnostic tool. As a PhD candidate on this project, you will apply state-of-the-art machine-learning based methodology, particularly deep neural networks and disease progression modeling, to address key challenges in FTD diagnosis.
If you have your own ideas for a medical imaging analysis MSc project, feel free to contact dr. Stefan Klein.